'Grey's Anatomy' Cast Looks Very Different After All These Years

The "Grey's Anatomy" cast looked a lot different back in the day.

Season 10 of the hit ABC series is debuting tonight (Sept. 26) at 9 p.m. EST, and we must say, the original cast members' transformations are incredible.

Take a look at the difference a few years makes by dragging the green button across the photos.

"Grey's Anatomy" Cast -- Season 2 vs. Season 10

Dr. Meredith Grey (Ellen Pompeo) -- Season 1 vs. Season 9

Dr. Derek Shepherd (Patrick Dempsey) -- Season 1 vs. Season 10

Dr. Cristina Yang (Sandra Oh) -- Season 1 vs. Season 9

Dr. Alex Karev (Justin Chambers) -- Season 1 vs. Season 9

Dr. Miranda Bailey (Chandra Wilson) -- Season 1 vs. Season 9

Dr. Richard Webber (James Pickens Jr.) -- Season 2 vs. Season 9

Dr. Callie Torres (Sara Ramirez) -- Season 2 vs. Season 9